Assessment of Response to Phototherapy in Neonatal Jaundice in a Tertiary Care Hospital in West Bengal, India

Authors

  • Samarpita Mukherjee Department of Biochemistry, College of Medicine & Sagore Dutta Hospital, Kamarhati, West Bengal, India
  • Arindam Sur Department of Biochemistry, R. G. Kar Medical College & Hospital, Kolkata, West Bengal, India
  • Sandip Kumar Mandal Department of Pediatrics, College of Medicine & Sagore Dutta Hospital, Kamarhati, West Bengal, India
  • Indranil Chakraborty Department of Biochemistry, JIS School of Medical Science and Research, Howrah, West Bengal, India

DOI:

https://doi.org/10.31344/ijhhs.v10i2.934

Keywords:

Total Bilirubin, unconjugated Bilirubin, delta Bilirubin, phototherapy, neonatal jaundice

Abstract

Most of the neonates suffer from unconjugated hyperbilirubinemia due to rapid destruction of fetal haemoglobin. This condition is successfully treated by phototherapy. A descriptive, cross-sectional study was conducted in the Department of Biochemistry, College of Medicine and Sagore Dutta Hospital, West Bengal, India, in collaboration with Department of Pediatrics, to compare unconjugated bilirubin versus total bilirubin in neonates over the course of treatment and to determine which one is best prognostic marker in phototherapy. Blood samples were collected from 148 neonates with jaundice undergoing phototherapy for unconjugated hyperbilirubinemia on commencement of phototherapy i.e., 3rd and 5th, 7th days of commencement of phototherapy and their unconjugated bilirubin, conjugated bilirubin and total bilirubin were measured using micro slide technology on Vitros 250 Dry Chemistry analyzer. All the neonates were thoroughly clinically evaluated to monitor the prognosis of phototherapy. Over the days, mean values of unconjugated bilirubin of the 1st, 2nd and 3rd samples of neonates showed a significant decrease (p<0.001), when baby undergoes successful phototherapy; however, the total bilirubin showed no significant change (p>0.05). In case of delta bilirubin, we did not find any statistically significant findings in any within group or between group comparisons (p>0.05).

International Journal of Human and Health Sciences Vol. 10 No. 02 Apr’26 Page: 92-98

Downloads

Published

2026-04-03

How to Cite

Mukherjee, S., Sur, A., Mandal, S. K., & Chakraborty, I. (2026). Assessment of Response to Phototherapy in Neonatal Jaundice in a Tertiary Care Hospital in West Bengal, India. International Journal of Human and Health Sciences (IJHHS), 10(2), 92–98. https://doi.org/10.31344/ijhhs.v10i2.934

Issue

Vol. 10 No. 2 (2026)

Section

Original Articles

License

Copyright (c) 2026 Samarpita Mukherjee, Arindam Sur, Sandip Kumar Mandal, Indranil Chakraborty

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Authors who publish in the International Journal of Human and Health Sciences agree to the following terms that:

  1. Authors retain copyright and grant International Journal of Human and Health Sciences the right of first publication of the work.

  2. Creative Commons Licence
    Articles in International Journal of Human and Health Sciences are licensed under a Creative Commons Attribution 4.0 International License CC BY-4.0.This license permits use, distribution and reproduction in any medium, provided the original work is properly cited.
  3. Authors are able to enter into separate, additional contractual arrangements for the distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
  4. Authors are permitted to post their work online (e.g., in institutional repositories or on their website) as it can lead to productive exchanges, as well as greater citation of published work.