Overview of Hepatitis B and Human Immunodeficiency Virus Coinfection

Authors

  • Solomon M Gamde Department of Medical Laboratory Science, Plateau State University, Bokkos, Plateau State, Nigeria
  • Shammah Joy Yakon Department of Medical Laboratory Science, Bingham University, New Karu, Nasarawa State, Nigeria
  • Abigail Abi Daniel Department of Public Health, Community Medicine and Primary Health Care, Bingham University, New Karu, Nasarawa State, Nigeria
  • Philip Alexandra Department of Microbiology, Bingham University, New Karu, Nasarawa State, Nigeria
  • Ajide A Bukola Department of Microbiology, Bingham University, New Karu, Nasarawa State, Nigeria

DOI:

https://doi.org/10.31344/ijhhs.v9i4.861

Keywords:

Hepatits B virus, human immunodeficency virus, immunology, pathology, Community Medicine and Primary Health, Microbiology

Abstract

Hepatitis B Virus (HBV) and Human Immunodeficiency Virus (HIV) co-infection is a major public health issue, especially in areas where both viruses are common. Despite the serious health problems associated with having both HBV and HIV, the specific immune interactions between these viruses are not fully understood. This review looks at how these two viruses interact in the body, affecting the immune system and overall health. When someone has both infections, it can lead to faster damage to the immune system, higher levels of virus in the body, and more severe liver problems, including cirrhosis and liver cancer. This research should aim to identify specific immune responses, which could lead to better treatment options for people with both infections. Improved understanding may also help with vaccine development and optimize the use of current antiviral treatments. Treatments like antiretroviral therapy, which can help manage both HBV and HIV, have shown effectiveness. However, treating both infections at the same time is complicated due to issues like drug resistance, a condition known as immune reconstitution inflammatory syndrome (IRIS), and overlapping side effects from the medications. This review also points out important gaps in research, especially regarding the long-term effects of having both infections and how to improve treatment plans for better patient outcomes. Future research should focus on new treatment methods, the role of immune boosters, and personalized treatment strategies to tackle the unique challenges of HBV-HIV co-infection.

International Journal of Human and Health Sciences Vol. 09 No. 04 Oct’25 Page: 200-206

 

Author Biographies

Solomon M Gamde, Department of Medical Laboratory Science, Plateau State University, Bokkos, Plateau State, Nigeria

 

 

Shammah Joy Yakon, Department of Medical Laboratory Science, Bingham University, New Karu, Nasarawa State, Nigeria

 

 

Abigail Abi Daniel, Department of Public Health, Community Medicine and Primary Health Care, Bingham University, New Karu, Nasarawa State, Nigeria

 

 

Philip Alexandra, Department of Microbiology, Bingham University, New Karu, Nasarawa State, Nigeria

 

 

Ajide A Bukola, Department of Microbiology, Bingham University, New Karu, Nasarawa State, Nigeria

 

 

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Published

2025-11-01

How to Cite

Gamde, S. M., Yakon, S. J., Daniel, A. A., Alexandra, P., & Bukola, A. A. (2025). Overview of Hepatitis B and Human Immunodeficiency Virus Coinfection. International Journal of Human and Health Sciences (IJHHS), 9(4), 200–206. https://doi.org/10.31344/ijhhs.v9i4.861

Issue

Vol. 9 No. 4 (2025)

Section

Review Articles

License

Copyright (c) 2025 Solomon M Gamde, Shammah Joy Yakon, Abigail Abi Daniel, Philip Alexandra, Ajide A Bukola

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