Is Hypereosinophilia A Sign of Underlying Tuberculosis? A Case Report and Review of Literature

Authors

  • Majed Abdul Basit Momin Department of Laboratory Medicine, Yashoda Hospitals, Malakpet Branch, Hyderabad, Telangana State, India
  • Abhijeet Ingle Department of Laboratory Medicine, Yashoda Hospitals, Malakpet Branch, Hyderabad, Telangana State, India
  • G Vamshi Krishna Reddy Department of Medical Oncology, Yashoda Hospitals, Malakpet Branch, Hyderabad, Telangana State, India
  • R Rahul Dev Singh Department of Laboratory Medicine, Yashoda Hospitals, Malakpet Branch, Hyderabad, Telangana State, India
  • Rubina Hassan Department of Laboratory Medicine, Yashoda Hospitals, Malakpet Branch, Hyderabad, Telangana State, India

DOI:

https://doi.org/10.31344/ijhhs.v7i3.584

Keywords:

Hypereosinophilia, inguinal tuberculosis, hepatic necrosis

Abstract

Eosinophilia is a common haematological problem that we see in our clinical practice. It is unusual to find hypereosinophilia at the onset of inguinal tuberculous lymphadenitis and hepatic non-granulomatous eosinophilic necrosis. We present the case of a 67-yearold man who complained of a dry cough for three months and a fever for one month. The right inguinal lymph node was palpable on clinical examination and initial haematological investigation revealed marked hypereosinophilia, mimicking myeloproliferative disorder. A thorough imaging workup revealed extensive thoracic lymphadenopathy as well as multiple liver lesions. Further liver mass core biopsy revealed hepatic, non-granulomatous necrosis with eosinophilic infiltration, whereas excision biopsy of inguinal lymph node revealed granulomatous inflammation with positive acid-fast bacili on histopathological examination. The patient responded to anti-tubercular treatment with steroids and hydroxyurea. The case emphasizes the association of eosinophilia in tuberculosis with tendency to forming mass lesions in liver and also the role of eosinophilic proteins in tissue injury.

International Journal of Human and Health Sciences Vol. 07 No. 03 Jul’23 Page: 262-266

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Published

2023-07-29

How to Cite

Basit Momin, M. A., Ingle, A., Krishna Reddy, G. V., Dev Singh, R. R., & Hassan, R. (2023). Is Hypereosinophilia A Sign of Underlying Tuberculosis? A Case Report and Review of Literature. International Journal of Human and Health Sciences (IJHHS), 7(3), 262–266. https://doi.org/10.31344/ijhhs.v7i3.584

Issue

Vol. 7 No. 3 (2023)

Section

Case Report

License

Copyright (c) 2023 Majed Abdul Basit Momin, Abhijeet Ingle, G Vamshi Krishna Reddy, R Rahul Dev Singh, Rubina Hassan

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