Biological Mechanisms Underlying Addiction

Ilhan Yargic


Addiction is a behavioral disorder related to alterations in neurobiological systems involved in reward system, brain stress response, physical withdrawal, inhibition and executive control. Alcohol or drug addiction does not occur without using these substances but genetic and epigenetic variations in these neurobiological systems cause individual differences. The current review summarizes the literature on the biological basis of drug addiction. In addition, this review tries to explain the path from occasional recreational substance use to the compulsive, addicted state. It will help understand why avoiding psychoactive drugs or not to start using is very crucial.

International Journal of Human and Health Sciences Vol. 02 No. 03 July’18. Page : 107-111


addiction; mechanism; abuse; dependence; neurobiology

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