An Unpropitious Surprise Post Vaginal Hysterectomy – A Case of Incidentally Discovered Extra-Gastrointestinal Stromal Tumour

Authors

  • Jessica Minal Department of Pathology, Dr Chandramma Dayananda Sagar Institute of Medical Education and Research, Dayananda Sagar University, Karnataka, India
  • Nikhil P V Department of Pathology, Dr Chandramma Dayananda Sagar Institute of Medical Education and Research, Dayananda Sagar University, Karnataka, India
  • Bhargavi Kalburgi Nagabhushan Trident Diagnostics and Healthcare Pvt Ltd. Jagajyothi Nagara, Nagadevanahalli, Bengaluru, Karnataka, India
  • Nirupama Murali Department of Pathology, Dr Chandramma Dayananda Sagar Institute of Medical Education and Research, Dayananda Sagar University, Karnataka, India
  • Nidha Gaffoor Department of Pathology, Dr Chandramma Dayananda Sagar Institute of Medical Education and Research, Dayananda Sagar University, Karnataka, India

DOI:

https://doi.org/10.31344/ijhhs.v8i2.645

Keywords:

Abdominal neoplasms, CD117 antigen, Immunohistochemistry, Pathology, DOG1, Gynaecology

Abstract

Extra-gastrointestinal stromal tumours (EGIST) are rare mesenchymal tumours that arise outside the gastrointestinal tract and mainly affect the omentum, mesentery, and retroperitoneum. We report a case of EGIST in an elderly female patient at an unusual location. The patient was referred to our centre with hemoperitoneum post vaginal hysterectomy for the treatment of third-degree utero-vaginal prolapse. Ultrasonography (USG) of abdomen and pelvis was done which revealed a heterogenous tumour in the upper abdomen. The tumour mass measured 23x18x8.5cms and was abutting the greater curvature of stomach without infiltration. A diagnosis of extra-gastrointestinal stromal tumour, spindle cell type, high grade, with pseudo signet ring appearance was rendered based on the morphology and immunohistochemistry with CD117(c-kit) and DOG1. Rupture of cancerous mass in the abdomen is one of the causes to be kept in mind in hemoperitoneum and EGIST should be considered in the differential diagnosis of large, multi-nodular, primary lesions of the abdomen. A high degree of suspicion is needed as these patients present late and are often diagnosed incidentally during investigations for unrelated medical conditions. 10% of EGISTs are primarily disseminated and the site of origin cannot be established with certainty, emphasizing the enigma of its origin as encountered in the present case.

International Journal of Human and Health Sciences Vol. 08 No. 02 Apr’24 Page: 207-211

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Published

2024-05-12

How to Cite

Minal, J., P V, N., Nagabhushan, B. K., Murali, N., & Gaffoor, N. (2024). An Unpropitious Surprise Post Vaginal Hysterectomy – A Case of Incidentally Discovered Extra-Gastrointestinal Stromal Tumour. International Journal of Human and Health Sciences (IJHHS), 8(2), 207–211. https://doi.org/10.31344/ijhhs.v8i2.645

Issue

Vol. 8 No. 2 (2024)

Section

Case Report

License

Copyright (c) 2024 Jessica Minal, Nikhil P V, Bhargavi Kalburgi Nagabhushan, Nirupama Murali, Nidha Gaffoor

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