Molecular Genetics of Cancer

Authors

  • Le D M.S, Affiliated with Baylor College of Medicine
  • Chen K MS1, Baylor College of Medicine
  • Husain S MS4, LMU-Debusk College of Osteopathic Medicine
  • Marathe A MS1, Baylor College of Medicine
  • Haq M Medical Oncologist and Clinical Instructor, Baylor College of Medicine

DOI:

https://doi.org/10.31344/ijhhs.v2i4.56

Keywords:

Cancer, Molecular Abnormalities, Genetics, Chromosomal Abnormalities, Carcinogenesis, Genetic Abnormalities, Therapeutic Interventions Molecular Genetics, Cancer Genome, Mutations, Oncogenes, Tumor Suppressor Genes

Abstract

Cancer is an unchecked cellular proliferation. It develops from a single cell with gene mutations, causing tumor growth and propagation. The genetic changes persist in the progeny of the initial cancer stem cell. Recent research has uncovered some of the mechanisms involved in the development and progression of cancer. Understanding the mechanisms of genetic mutations and their actions allows scientists to interrupt these aberrant genetic pathways and treat these diseases. This review briefly discusses evolution of knowledge in the field, technologies involved, molecular changes caused by the aberrant cancer genes, and pathways of therapeutic interventions.

International Journal of Human and Health Sciences Vol. 02 No. 04 October’18. Page : 199-208

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Published

2018-08-29

How to Cite

D, L., K, C., S, H., A, M., & M, H. (2018). Molecular Genetics of Cancer. International Journal of Human and Health Sciences (IJHHS), 2(4), 199–208. https://doi.org/10.31344/ijhhs.v2i4.56

Issue

Section

Review Articles