Predictive factors for severe COVID-19 infection in Terengganu state of Malaysia

Authors

  • Hafizuddin Awang Besut District Health Office, Kampung Raja, Besut, Terengganu, Malaysia
  • Mohd Hanief Ahmad Setiu District Health Office, Bandar Permaisuri, Setiu, Terengganu, Malaysia
  • Kamarul Azhar Mohamed Setiu District Health Office, Bandar Permaisuri, Setiu, Terengganu, Malaysia
  • Azmani Wahab Terengganu State Health Department, Kuala Terengganu, Terengganu, Malaysia
  • Norafidah Abdul Rashid Terengganu State Health Department, Kuala Terengganu, Terengganu, Malaysia
  • Hasnan Arwit Terengganu State Health Department, Kuala Terengganu, Terengganu, Malaysia
  • Mohd Anuar Abd Rahman Terengganu State Health Department, Kuala Terengganu, Terengganu, Malaysia
  • Kasemani Embong Terengganu State Health Department, Kuala Terengganu, Terengganu, Malaysia

DOI:

https://doi.org/10.31344/ijhhs.v6i3.457

Keywords:

COVID-19, severe infection, fever, comorbidity, Malaysia.

Abstract

Background: COVID-19 has a varied clinical presentation and may progress to severe form which could be fatal. Determination of risk factors for severe infection would be beneficial in averting COVID-19 mortality in Terengganu setting.

Materials and Methods: A casecontrol study between mild and severe COVID-19 groups was conducted in Terengganu state from 1st March 2020 until 31st January 2021 based on retrospective record review. Individuals with laboratory RT-PCR confirmed positive test for COVID-19 were included as study samples. Descriptive statistics, simple and multiple logistic regression analyses were employed for statistical analysis.

Results: There were 2142 COVID-19 cases in Terengganu during the studied period. The proportion of severe COVID-19 infection was 2.1% (95%CI: 0.01, 0.03). Among the severe COVID-19 cases, their mean (±SD) age was 52 (±16) and majority of them were male (59.1%) and had comorbidity (56.8%). The common symptoms among severe COVID-19 cases included fever (68.2%), cough (63.6%), coryza (22.7%), sore throat (13.6%) and anosmia (11.4%). Multiple logistic regression revealed older age, presence of comorbidity, having symptoms of fever, cough and anosmia as the significant associated factors for severe COVID-19 with adjusted odds ratio (AOR) of 1.07 (95%CI: 1.03, 1.11), p<0.001; AOR 5.97 (95%CI: 2.09, 17.01), p=0.001; AOR 4.78 (95%CI: 1.63, 14.05), p=0.004; AOR 4.81 (95%CI: 1.70, 13.60), p=0.003; and AOR 8.39 (95%CI: 1.39, 50.33), p=0.020,respectively.

Conclusion: Knowing the predictive factors for severe COVID-19 would facilitate clinicians in timely identification of high-risk cases for delivering prompt treatment and intervention.

International Journal of Human and Health Sciences Vol. 06 No. 03 July’22 Page: 269-274

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Published

2022-06-13

How to Cite

Awang, H., Ahmad, M. H., Mohamed, K. A., Wahab, A., Rashid, N. A., Arwit, H., … Embong, K. (2022). Predictive factors for severe COVID-19 infection in Terengganu state of Malaysia. International Journal of Human and Health Sciences (IJHHS), 6(3), 269–274. https://doi.org/10.31344/ijhhs.v6i3.457

Issue

Vol. 6 No. 3 (2022)

Section

Original Articles

License

Copyright (c) 2022 Hafizuddin Awang, Mohd Hanief Ahmad, Kamarul Azhar Mohamed, Azmani Wahab, Norafidah Abdul Rashid, Hasnan Arwit, Mohd Anuar Abd Rahman, Kasemani Embong

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