Evaluation of SD Bioline Malaria Antigen Plasmodium Falciparum / Panmalarial for Diagnosis of Malaria in Hospital Raja Permaisuri Bainun Ipoh

Authors

  • Priyaasaro Sevakumaran Department of Health Science, Faculty of Engineering and Life Science, Universiti Selangor Shah Alam and Microbiology Unit, Pathology Department of Hospital Raja Permaisuri Bainun, Ipoh

DOI:

https://doi.org/10.31344/ijhhs.v0i0.165

Keywords:

Malaria, Plasmodium, Rapid Diagnosis Tests, SD Bioline Malaria Antigen Plasmodium falciparum/ Panmalarial

Abstract

Introduction: Rapid Diagnostic Tests (RDTs) for malaria has improved malaria manageme nt.

Objectives: This study was conducted to evaluate the performance of SD Bioline Malaria Antigen Plasmodium falciparum/Panmalarial compared to gold standard microscopy using Giemsa staining for diagnosis of malaria in Hospital Raja Permaisuri Bainun Ipoh.

Method: Microscopy and RDT diagnosis were performed on 377 blood samples. In this study, the SD Bioline Malaria Antigen Plasmodium falciparum/Panmalarial Rapid Diagnostic Tests (RDT) detecting Histidine Rich Protein II and Plasmodium lactate dehydrogenase antigens were used. Blood film malaria parasite examination was carried out as the reference.

Results: Malaria parasites were identified by microscopy in 61 individuals and RDT positively tested in 27 (44.3%) patients. The sensitivity and specificity of SD Bioline Malaria Antigen Plasmodium falciparum/Panmalarial was 44.2% (95% CI, 31.8 to 57.5) and 100% (95% CI, 98.6 to 100.0) respectively. The positive predictive value (PPV) for SD Bioline Malaria Antigen Plasmodium falciparum/Panmalarial was 100% (95% CI, 84.5 to 100) and the negative predictive value (NPV) was 90% (95% CI, 86.6 to 93.1).

Discussion: The SD Bioline Malaria Antigen Plasmodium falciparum/ Panmalarial test showed excellent results in the diagnosis of endemic Plasmodium falciparum infections. This SD Bioline Antigen Plasmodium falciparum/ Panmalarial loses validity for low parasitemia. These results confirm the validity of SD Bioline Antigen Plasmodium falciparum/ Panmalarial in malaria diagnosis must be complemented by microscopy.

Conclusion: This examination has demonstrated that the SD Bioline Malaria Antigen Plasmodium falciparum/ Panmalarial cannot be utilized as an elective strategy contrasted with the best quality level Giemsa staining (BFMP). These outcomes affirm that whenever supplemented by microscopy, SD Bioline Malaria Antigen Plasmodium falciparum/ Panmalarial are substantial in malaria analysis.

International Journal of Human and Health Sciences Supplementary Issue: 2019 Page: 47

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Published

2019-12-07

How to Cite

Sevakumaran, P. (2019). Evaluation of SD Bioline Malaria Antigen Plasmodium Falciparum / Panmalarial for Diagnosis of Malaria in Hospital Raja Permaisuri Bainun Ipoh. International Journal of Human and Health Sciences (IJHHS), 47. https://doi.org/10.31344/ijhhs.v0i0.165

Issue

2019: Supplementary Issue: 2019

Section

E-Poster Presentation Abstracts

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